KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
5.45
Human Site:
S58
Identified Species:
8
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
S58
P
A
A
T
P
R
Q
S
L
G
H
P
P
P
E
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
T116
R
F
G
H
E
G
R
T
W
G
D
L
G
A
A
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
T97
R
F
G
H
E
G
R
T
W
G
D
A
G
A
S
Dog
Lupus familis
XP_541890
401
45078
S58
P
A
A
P
P
S
G
S
Q
G
L
E
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
F57
F
I
V
S
P
T
T
F
H
T
Q
E
S
S
A
Rat
Rattus norvegicus
P12368
401
45522
F58
F
I
A
P
P
T
T
F
H
A
Q
E
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
E30
E
A
Y
N
P
D
E
E
E
D
D
A
E
S
R
Chicken
Gallus gallus
Q5ZM91
382
43332
R56
F
L
R
E
Y
F
E
R
L
E
K
E
E
T
K
Frog
Xenopus laevis
NP_001084637
402
45172
F57
S
H
G
M
G
L
P
F
S
L
T
K
G
V
N
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
K57
A
A
A
K
T
G
G
K
G
V
M
F
D
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
L63
D
Q
S
T
D
D
Q
L
S
V
N
S
Q
D
A
Honey Bee
Apis mellifera
XP_392905
383
43849
S64
D
P
A
Q
T
T
T
S
T
P
D
E
S
V
D
Nematode Worm
Caenorhab. elegans
P30625
366
41449
Q55
H
F
E
K
L
N
E
Q
R
A
Q
E
G
G
N
Sea Urchin
Strong. purpuratus
Q26619
369
41770
P57
R
G
V
T
F
T
A
P
E
D
A
E
S
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
P90
S
S
V
M
F
K
S
P
F
V
N
E
D
P
H
Red Bread Mold
Neurospora crassa
Q01386
385
42138
S67
G
F
G
G
D
A
P
S
D
M
P
V
R
R
Q
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
6.6
6.6
46.6
N.A.
6.6
13.3
N.A.
13.3
6.6
0
20
N.A.
13.3
13.3
0
6.6
P-Site Similarity:
100
20
20
46.6
N.A.
13.3
13.3
N.A.
20
20
0
20
N.A.
26.6
20
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
25
32
0
0
7
7
0
0
13
7
13
0
13
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
13
13
0
0
7
13
25
0
13
13
7
% D
% Glu:
7
0
7
7
13
0
19
7
13
7
0
50
13
0
13
% E
% Phe:
19
25
0
0
13
7
0
19
7
0
0
7
0
0
0
% F
% Gly:
7
7
25
7
7
19
13
0
7
25
0
0
25
13
7
% G
% His:
7
7
0
13
0
0
0
0
13
0
7
0
0
0
7
% H
% Ile:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
13
0
7
0
7
0
0
7
7
0
0
7
% K
% Leu:
0
7
0
0
7
7
0
7
13
7
7
7
0
0
0
% L
% Met:
0
0
0
13
0
0
0
0
0
7
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
0
0
0
13
0
0
0
13
% N
% Pro:
13
7
0
13
32
0
13
13
0
7
7
7
13
13
7
% P
% Gln:
0
7
0
7
0
0
13
7
7
0
19
0
7
0
7
% Q
% Arg:
19
0
7
0
0
7
13
7
7
0
0
0
7
7
7
% R
% Ser:
13
7
7
7
0
7
7
25
13
0
0
7
25
25
7
% S
% Thr:
0
0
0
19
13
25
19
13
7
7
7
0
0
7
0
% T
% Val:
0
0
19
0
0
0
0
0
0
19
0
7
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _